Creatine in Clinical Perspective

Creatine is best known as a sports supplement, yet its clinical relevance extends far beyond athletic performance. As an endogenous compound involved in cellular energy transfer, creatine influences skeletal muscle, brain function, and metabolic resilience—areas of growing interest in medical practice.

This ebook examines creatine from a clinical perspective. It reviews the evidence on supplementation for sarcopenia and age-related muscle loss, potential cognitive and neurological effects, metabolic implications, safety considerations across different patient populations, and practical guidance on dosing and use in real-world clinical settings.

Written for clinicians, healthcare professionals, and informed readers, Creatine in Clinical Perspective provides a clear, evidence-based synthesis of what is known, what remains uncertain, and how creatine may fit into broader strategies for supporting muscle health, metabolic function, and patient outcomes—without overstating benefits or overlooking limitations.